No, the Geforce cards don't have a limitation with 4K media and the GPU acceleration. The GPU acceleration ie CUDA is not specific to either Geforce or Quadro. The specs of the cards decide the performance. The Geforce Specs are far greater than the Quadro K5000 if you get the 780Ti or the Titan Black Edition. Both cards are cheaper. The only benefit the Quadro card has in regards to Adobe is the 10bit color output option for preview since Adobe is Open GL based for the API. However you can get a Blackmagic 4K studio card with a Titan Black edition and still spend less money than the K5000 while having far better performance. I personally run a E5-2697 V2 12 Core Xeon with a 770GTX 4GB card and I play 4K r3d back at half resolution easily right now. Full resolution for preview with 4K red is simply not possible via any software other than Redcine X Pro right now until the GPU acceleration debayering is available. BTW I would suggest 1 Titan Black edition over 2x 770GTX cards. The scaling across GPU's only works on rendering right now. When the GPU acceleration debayer is available then adding a 2nd Titan card would be far better than having 2x 770GTX cards.
SLI and GPU acceleration are 2 different technologies. SLI is scaling the drawing to the display across more than 1 video card. GPU acceleration is a programming module that send calculations to the GPU for processing that were normally processed by the player via the CPU. GPU acceleration does not require or even use SLI to scale across GPU's. That is managed and scheduled by the application.
Eric
ADK